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Breakthrough Pain

Breakthrough pain is pain that comes on suddenly for short periods of time and is not alleviated by the patients' normal pain suppression management. It is common in cancer patients who commonly have a background level of pain controlled by medications, but the pain periodically "breaks through" the medication. The characteristics of breakthrough cancer pain vary from person to person, including the duration and possible causes.


Compare Drugs Taken for Breakthrough Pain (As determined from adverse event reports in AERS). Explain the table
* Please select up to 4 drugs.

Sample User Comments for "breakthrough pain" drugs

Side Effects: headaches, nausea , druggy feelings, heaviness, just an overall sense of malaise. Felt like I was in a drug induced stupor. Very uncomfortable and unacceptable.

Did the author experience nausea while taking acetaminophen; hydrocodone bitartrate?
Comment on dizziness while taking hydromorphone hydrochloride (View full report on hydromorphone hydrochloride related dizziness)
Side Effects: uncomfortably high and dizzy, very short acting, migraine rebound is equal or worse than originally

way too strong in knocking you out of it (i am used to fiorinal3 or tylenol...
Did the author experience dizziness while taking hydromorphone hydrochloride?
... hard time focusing and my motor skills are shakey and slow (almost like being drunk) but my mind runs at like 90mph and i talk alot and say things i would normally feel uncomfortable saying. it helps ...
Did the author experience discomfort while taking acetaminophen; hydrocodone bitartrate?
Comment on feeling drunk while taking tapentadol hydrochloride (View full report on tapentadol hydrochloride related feeling drunk)
Nucynta (tapentadol) for Pain: I have had many back surgeries for degenerated disc disease and was put on Nucynta three days ago. My dose is 50 mg 3 times a day. It makes me feel high gives me a sever...
Did the author experience feeling drunk while taking tapentadol hydrochloride?
Just started taking Vicodin this week for severe tooth, gum & jaw pain due to an absess while awaiting a root canal next week (OUCH!). It really works on pain and allows me to concentrate plus has a "...
Did the author experience pain in jaw while taking acetaminophen; hydrocodone bitartrate?
* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About AERS: The Adverse Event Reporting System (AERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into AERS. The AERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, AERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.