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Modafinil Related Drug Tolerance Increased

Official FDA Reports2
Social Media Events21
Active Ingredients
  • Modafinil
Additional Drug Brands and Names
Additional Terms for Drug Tolerance Increased
  • Escalating Tolerance
  • Can Build An Immunity To
  • Effectiveness Decreases Over Time
  • Decreases In Effectiveness Over Time
  • Helped For Awhile Not Helping Know
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  This report is for all products sharing this active ingredient. For more details, please use our Workbench for research on individual brands like Provigil.


Explanation

The quarterly trend chart illustrates changing levels of adverse events over time. Results from both the FDA Adverse Event Database (AERS) and adverse events extracted from social media by Druginformer are plotted side-by-side for easy comparison.


List of Possible Side Effects Reported

Report Date Dosage Indication Outcome Country Gender Age Weight (lbs)

* DrugInformer calculates alarm using a proprietary algorithm. Alarm should not be taken as an ofiicial signal from the FDA or other regulatory entity.


Social Media Comments From Around the Web

The following are comments from users that experienced side effects while taking Milnacipran Hydrochloride

Provigil

... but got many side effects. Unlike antidepressants, Provigil /Modafinal can be taken as needed, and works immediately, so I have tapered off of the daily dose (it does stop working after a while,) a...


Source:" Provigil Oral : User Ratings covering ...

View full report on drug related drug tolerance increased

Did the author experience drug tolerance increased while taking provigil?

What is this?

Modafinil

... I was first in line. changed my life completely; I was normal again; I could produce again and did to a stunning degree. 3 weeks ago, after 8 years, Provigil completely stopped working . I know all th...


Source:" comments/modafinil/provigil.html&sa=U&...

View full report on drug related drug tolerance increased

Did the author experience drug tolerance increased while taking modafinil?

What is this?

Provigil

Side Effects: dry mouth

It helped at first. I was taking nuvigil, but it stopped working so the doctor put me on provigil instead so I could take it more than once a day. The effects were...


Source:" PROVIGIL: Side effects, ratings, and p...

View full report on drug related drug tolerance increased

Did the author experience drug tolerance increased while taking provigil?

What is this?

Tell us about your Experience with Modafinil Related Drug Tolerance Increased

Thank you for sharing your experience with us!

Share Your Experience

Druginformer Identified Side Effects: Abnormal weight gain, Drug tolerance increased

Posted By marie in fdb.rxlist.com on November 27, 2013 @ 12:00 am

I had chronic fatigue after a Lyme-type disease, then stopped walking, got depressed, gained weight, and got breast cancer. Treated with two surgeries and had radiation-related fatigue. I am a nurse w...

Druginformer Identified Side Effects: Drug ineffective, Drug tolerance increased

Posted By Anonymous in drugs.com on November 28, 2012 @ 12:00 am

Had no life at all except pain and overwhelming fatigue for 10 years. Visited many doctors with no help at all. I am a scientist began tracking medicines that were in the pipeline - came across Provi...

Druginformer Identified Side Effects: Drug ineffective, Dry mouth, Weight decreased, Drug tolerance increased

Posted By Anonymous in askapatient.com on November 30, 2011 @ 12:00 am

... I was taking nuvigil, but it stopped working so the doctor put me on provigil instead so I could take it more than once a day. The effects were similar, but this dosage is not working again. I am o...

Druginformer Identified Side Effects: Nausea, Drug tolerance increased

Posted By dozy in drugs.com on July 28, 2009 @ 12:00 am

Provigil (modafinil) for Narcolepsy: I was diagnosed with Narcolepsy about 2 weeks ago. For 2 months I had been nodding off at work and at home, it got really bad when I nodded off while at a stopligh...

Druginformer Identified Side Effects: Nausea, Drug tolerance increased

Posted By Anonymous in drugs.com on July 28, 2009 @ 12:00 am

I was diagnosed with Narcolepsy about 2 weeks ago. For 2 months I had been nodding off at work and at home, it got really bad when I nodded off while at a stoplight driving and when I got "written" up...

Druginformer Identified Side Effects: Drug tolerance increased

Posted By Anonymous in fdb.rxlist.com on April 12, 2009 @ 12:00 am

I was Prescribed Provigil for CFS and Fibromyalgia. It made me feel like I had a new life for the first 2 months and then suddenly stopped working. I was told by my M D that this is a common occurrenc...

Druginformer Identified Side Effects: Drug tolerance increased

Posted By Anonymous in everydayhealth.com on April 6, 2008 @ 12:00 am

Provigil helped relieve my symptoms of treatment resistant depression--it was very effective for over a year. But, it suddenly stopped working. I did not experience and side effects with this medicati...

Druginformer Identified Side Effects: Lethargy, Drug ineffective, Drug tolerance increased

Posted By Anonymous in everydayhealth.com on April 7, 2007 @ 12:00 am

etter than nothing I suffer from hypersomnia, and I literally cannot function without it, but it still doesn't help nearly enough. And I've found that it stops working after a while, then if I go for...

Druginformer Identified Side Effects: Confusional state, Diarrhoea, Hyperhidrosis, Insomnia, Irritability, Drug tolerance increased

Posted By Anonymous in askapatient.com on November 6, 2006 @ 12:00 am

Side Effects: Sleeplessness (Day 1), sweating, diarrhea, confusion, rambling, irritation, stopped working at day 5 At first it seemed to be working well, except by day 3 I noticed that it w...

Druginformer Identified Side Effects: Drug tolerance increased

Posted By Anonymous in everydayhealth.com on May 13, 2006 @ 12:00 am

Worked great for about two years I found that Provigil worked extremely well, without side effects for me for about two years. It simply stopped working after a while, and as it is very expensive, an...



* Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition.

* About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. The FAERS database may contain duplicate reports, the report quality is variable, and many factors may influence reporting (e.g., media attention, length of time a drug is marketed, market share). For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products.